St Justin Martyr (AD 100–ca.165)
[Jesus] became man by the Virgin so that the course that was taken by disobedience in the beginning through the agency of the serpent might be also the very course by which it would be put down. Eve, a virgin and undefiled, conceived the word of the serpent and bore disobedience and death. But the Virgin Mary received faith and joy when the angel Gabriel announced to her the glad tidings that the Spirit of the Lord would come upon her and the power of the Most High would overshadow her, for which reason the Holy One being born of her is the Son of God. And she replied, “Be it done unto me according to your word” (Luke 1:38) (Dialogue with Trypho 100 [A.D. 155])
St Irenaeus (AD 130–ca.202)
Consequently, then, Mary the Virgin is found to be obedient, saying, “Behold, 0 Lord, your handmaid; be it done to me according to your word.” Eve . . . who was then still a virgin although she had Adam for a husband — for in paradise they were both naked but were not ashamed; for, having been created only a short time, they had no understanding of the procreation of children . . . having become disobedient [sin], was made the cause of death for herself and for the whole human race; so also Mary, betrothed to a man but nevertheless still a virgin, being obedient [no sin], was made the cause of salvation for herself and for the whole human race. . . . Thus, the knot of Eve’s disobedience was loosed by the obedience of Mary. What the virgin Eve had bound in unbelief, the Virgin Mary loosed through faith (Against Heresies 3:22:24 [A.D. 189]).